The world of psychedelic use is rapidly expanding, with more and more people turning to the mind-expanding effects of these substances. As we learn more about how they work, it has become clear that there are many potential benefits associated with taking psychedelics, but there are also some risks involved as well.

In this post we’re going to discuss why CBD can be a best friend when it comes to reducing the side effects of psychedelics.

psychedelics cbd endocannabinoid trip



CBD is a non-psychoactive plant cannabinoid that is found primarily in hemp and cannabis. It has a wide range of benefits, but the one we’re interested in today is its ability to help reduce the side effects from taking psychedelics.

CBD does not have any psychoactive effects and because it's not an addictive substance, you won't be getting high on this one (not that there's anything wrong with that). CBD provides an array of health benefits including pain relief, anxiety reduction, and even cancer relief! If you're looking for something new to spice up your life or just want something that can help with your energy levels while taking psychedelics - check out our Spekr Psychedelic Care Products.


Anxiety is a tough thing to deal with. It can be tough to manage and makes everyday life feel like a struggle. Luckily, there's CBD!

CBD is a natural anti-anxiety medication that can help you if you're struggling with social anxiety, panic attacks, or general day-to-day fears. If you're feeling anxious right now and want something that actually works without side effects or having to take another prescription drug (or five), then CBD might be your best bet.


CBD is not a substitute for your regular treatment, but it can be extremely helpful in certain situations. If you have some kind of mental illness that requires medication like depression or anxiety, CBD can help take the edge off without making you feel high or paranoid.

Anxiety and paranoia are notoriously difficult states to treat because they're so subjective: even if you're feeling better after smoking weed (which is likely), another person could be more anxious than before due to their own mental state being different from yours!

If you're using psychedelics, you really should be using CBD.

CBD can help with all kinds of things. If your psychedelic use is causing you anxiety or paranoia, CBD can reduce that. It also helps improve sleep and reduces the risk of seizures. CBD is even useful if nausea is an issue for you—because it's so effective at reducing inflammation in the body, it reduces feelings of sickness while you're tripping on psychedelics.

psychedelics cbd endocannabinoid trip

In this post we’re going to discuss why CBD is your best friend when it comes to reducing the side effects of psychedelics.

  • CBD is a natural anti-inflammatory and can help with anxiety.
  • CBD helps to reduce nausea.
  • CBD can help you sleep better at night, because it’s relaxing and soothing.
  • CBD can help reduce paranoia, which is one of the main side effects of psychedelics.

How to incorporate CBD into your Psychedelics routine

While it’s not necessary to incorporate CBD into your psychedelic routine, it can be a great way to have a more safe and pleasant experience. Many people opt for oral or sublingual consumption of CBD before taking psychedelics. CBD is highly effective at reducing anxiety and stress while also allowing users more control over the intensity of their trip.

Why CBD is so good for Psychedelics

It’s a great idea to combine your psychedelics with CBD.

  • First, it helps with anxiety and nausea, which are common side effects of taking psychedelics.
  • Second, CBD can help reduce the risk of a bad trip by reducing the intensity of visual disturbances and other negative mental sensations associated with psychedelic use.
  • Third, it also reduces paranoia—a common trait among people who have used psychedelics in the past or currently use them regularly—and improves mood.

Next time you eat those magic mushrooms, make sure you have some CBD around.

The next time you eat those magic mushrooms, make sure to have some CBD around. You'll want to take this beforehand and after your trip, not just during.

CBD is a great way to reduce the side effects of psychedelics because it helps with anxiety, nausea, depression, and physical pain. You can take CBD either before or after taking psychedelics, depending on what's bothering you more at that moment.

psychedelics cbd endocannabinoid trip


The endocannabinoid system plays a huge part in how psychedelics work.

The endocannabinoid system is the master regulatory system and has a network of receptors that exist throughout the human body. These receptors are responsible for managing things like mood, pain, memory and appetite. In short: the endocannabinoid system is critical to your health and well-being.

Two psychedelics—LSD and ibogaine—have been shown to increase levels of anandamide (the “bliss molecule”) in rats’ brains by as much as 30%. Anandamide is an endocannabinoid—one of the chemicals produced naturally by our bodies that fits into these same receptors. So when you take psychedelics you activate this system directly by increasing levels of your own endocannabinoids or mimicking them directly with compounds such as THC or CBD.

The activation helps explain some of their effects: psychedelics can enhance visual acuity and make colors brighter; it also heightens intensity in music so that listening feels like being transported into another world (or coming home). Certain psychedelics have been shown to lead users through a psychedelic experience while also relieving withdrawal symptoms from opioid addiction; both have been shown to reduce depression symptoms over time.*

CBD can be used medicinally before or after a trip to help with any physical or mental ailments you may have.

Anecdotal reports suggest that using CBD before or after you trip could help with the physical side effects of psychedelic drugs such as nausea, muscle weakness and headaches. The mental effects are harder to predict because they vary from person to person depending on their sensitivity level to psychedelics.

Tryptophan helps balance serotonin levels post-trip.

Tryptophan, an essential amino acid, is a precursor to serotonin. Serotonin is an essential neurotransmitter that helps regulate mood and anxiety levels.

The process by which tryptophan converts into serotonin means that when you take psychedelics like LSD or psilocybin mushrooms (which both contain tryptamines), they'll stay in your system longer because they're competing with the tryptophan in your body for absorption. If there is less tryptophan available, then less of it will convert into serotonin—meaning more serotonin stays circulating through your brain after taking a psychedelic drug!

CBD can help to alleviate the visual disturbances caused by a bad trip.

CBD can help to alleviate the visual disturbances caused by a bad trip.

These kinds of side effects, known as "bad trips," are a common occurrence for those who have taken psychedelics. Some people experience euphoria and bliss; others find themselves in a dark place that they cannot escape from. If this happens to you, CBD will help reduce the intensity of these negative effects so that you can enjoy your psychedelic experience more fully.

CBD can also help reduce anxiety and paranoia by acting as an anxiolytic (anxiety-reducing) agent —and it may even cause a reduction in nausea when used with certain types of psychedelics.

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It has been revealed that CBD prevents panic attacks caused by the activation of 5-HT2A receptors.

It has been revealed that CBD prevents panic attacks caused by the activation of 5-HT2A receptors.

5-HT2A receptors are serotonin receptors that are activated by many psychedelics. They are also activated by CBD, which means that if you take some CBD before taking a psychedelic, it will reduce its effects on the body and mind.

Why CBD is so useful when using psychedelics

When you’re taking psychedelics, there are a variety of side effects to be aware of. These can include anxiety, paranoia, and more.

CBD is able to reduce the intensity of these effects by acting as an anxiolytic (anti-anxiety) agent. CBD also acts as an anti-psychotic by binding to 5HT1A receptors in your brain and reducing the psychosis-like symptoms caused by psychedelics.

In addition, studies have shown that CBD has neuroprotective properties that can help with any visual disturbances caused by psychedelics—such as hallucinations or seeing trails behind moving objects—by reducing excitotoxicity in the brain (which occurs when neurons are overstimulated and eventually die).

How to take CBD before a trip?

The best way to take CBD before a trip is to make sure it’s with you at all times.

  • Take your CBD with you, where ever you go.
  • Take CBD 30-60 minutes before ingesting psychedelic compounds.
  • Make sure to check the interactions between any medication you take and CBD.

Many people have discovered that one of the best potential uses for CBD is as a way to mitigate the side effects of psychedelic substances.

Many people have discovered that one of the best potential uses for CBD is as a way to mitigate the side effects of psychedelic substances. Before you take a trip, you can take some CBD to help calm your nerves and make sure that it’s going to be a good experience.

After you’re done tripping, taking some CBD is also a great way to help ease back into reality. It will help reduce any anxiety or discomfort from coming down from your trip, and it also has anti-inflammatory properties which can prevent soreness in your muscles after having been on your feet all day at Burning Man.


In this post we’ve discussed why CBD is your best friend when it comes to reducing the side effects of psychedelics.

Whilst we've only touched base on a few psychedelics in this post from the Spekr Library, CBD can help with all psychedelics, including psilocybin, MDMA, LSD, ibogaine, ketamine, DMT, and ayahuasca.

We hope that you enjoyed reading this post and that it has given you a better understanding of why CBD is such an important part of your trip. If there is anything else we can help with please feel free to leave a comment below or email us at team@spekr.co