In this clinical trial conducted in 2005, scientists explored the benefits of using a skincare products enriched with Vitamin E on the skin's antioxidant protection against photooxidative stress. The study discovered that using a product that contained alpha-tocopherol, the most biologically active form of vitamin E, had a protective effect on the skin barrier by shielding it from photooxidative stress. This is significant because the skin barrier plays a critical role in protecting the body from environmental stressors.
In this clinical trial, 13 healthy volunteers were asked to use a vitamin E-enriched product on one forearm and a placebo product on the other for three weeks. The researchers checked the levels of vitamin E and squalene on the skin before and after the study period. They discovered that using the vitamin E-enriched product increased the levels of vitamin E and squalene significantly, while the placebo product decreased these levels. Moreover, the study revealed that using the vitamin E-enriched product protected against UVA-induced photooxidation of squalene.
Overall, the results of this clinical trial suggest that using a skincare product with vitamin E can be beneficial for the skin's health, boosting vitamin E and squalene levels on the skin and providing antioxidant protection against harmful environmental factors.
Study Title: Vitamin E delivery to human skin by a rinse-off product: penetration of alpha-tocopherol versus wash-out effects of skin surface lipids
Study Link: https://pubmed.ncbi.nlm.nih.gov/15608499