A 2017 study found that a single dose of CBD, a non-psychoactive compound found in cannabis/hemp, can help lower blood pressure and the body's response to stress. This randomized, placebo-controlled, double-blind, crossover clinical trial was conducted on nine healthy male adults who were given a dose of either CBD or a placebo before undergoing stress tests that included cold exposure, mental stress, and exercise stress.
In this study, healthy male volunteers who had never previously used cannabis were given a single dose of 600mg CBD, and no adverse effects were reported during the study or in the following week. This indicates that a single dose of 600mg of CBD is well-tolerated and safe for healthy individuals. During each test, the researchers continuously monitored the participants' cardiovascular parameters, such as blood pressure, heart rate, and stroke volume. The researchers found that CBD reduced blood pressure during all three stress tests and that this effect was most pronounced during the cold stress test.
The results showed that those who had taken CBD had lower blood pressure during the stress tests and that the blood pressure response to stress was blunted, particularly in the pre- and post-stress periods. Additionally, the study found that CBD affected cardiac parameters, such as heart rate and stroke volume, but did not affect cardiac output.
Overall, there were no reported negative effects from taking CBD during the study or the following week. This study shows that taking a single dose of 600mg CBD has the potential to lower blood pressure and the response to stress, especially during cold stress. This might be because CBD helps to reduce anxiety and pain, and could also have a direct effect on heart health. It's important to consider these changes in blood pressure if you use CBD for health reasons. This study adds to the growing research on the potential benefits of CBD, which could have important implications for human health.
Study Title: A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study
Study Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470879